Carefully consider the placement of the patch to make sure that the temperature reading is aligned with the expected results. The average temperature reading of an oral thermometer in a healthy adult is 98.6°F (37°C), but measurements taken from other areas of the body differ in temperature. For example, a temporal thermometer reads a temperature that can be up to one degree (1°F) lower than that of an oral thermometer.

The crucial distinction here is between core temperature and skin temperature. The primary goal of this design is to demonstrate effective techniques for the measurement of skin temperature. The temperature at the surface of a patient's skin is not normally identical to the patient's core temperature. The most accurate methods of obtaining core temperature are internal, such as with oral or rectal thermometers. In certain applications, such as long-term patient monitoring in the incubator of a neonatal intensive care unit (NICU), skin temperature monitoring is often the only practical method. Skin temperature can also be used in conjunction with other parameters in applications such as fitness trackers and heart-rate monitors.

When using skin temperature to try and obtain a measurement close to core temperature, the preferred sites are traditionally the underarm (axillary) or the forehead (temporal). The form factor of this patch demonstrates a generic circular form that can be used anywhere on the skin. For axillary measurements, extending the TMP119 away from the primary portion of the board to allow the RF antenna to be exposed on one side while the sensor is enclosed underneath the user's arm can be desirable.

The effective Bluetooth range of the design depends on many factors, such as walls and objects between the patch and the smart device. When worn; however, the primary source of signal loss is likely the patch wearer. To improve the range, the CC2340R5 can be programed to increase the Bluetooth output power, but this decreases the battery life of the patch. Under normal operation, the patch is powered by a 3V coin cell; therefore, low-power Bluetooth modes are recommended to extend the operating time for this design. As characterized, this design uses the maximum output power of the CC2340R5 to attain a longer range. Alternatively, antenna and pi-network matching can be performed while the device is worn to increase the signal range without increasing the output power level of the CC2340R5.