Product details


Type Integrated Photoplethysmography (PPG) Number of input channels 1 Resolution (Bits) 24 Number of LEDs 3 Operating temperature range (C) -20 to 70 Interface type I2C open-in-new Find other Biosensing AFEs

Package | Pins | Size

DSBGA (YZP) 15 0 mm² 2.49 x 1.49 open-in-new Find other Biosensing AFEs


  • Transmitter:
    • Supports Common Anode LED Configuration
    • Dynamic Range: 100 dB
    • 6-Bit Programmable LED Current to 50 mA (Extendable to 100 mA)
    • Programmable LED On-Time
    • Simultaneous Support of 3 LEDs for Optimized SPO2, HRM, or Multi-Wavelength HRM
  • Receiver:
    • 24-Bit Representation of the Current Input from a Photodiode in Twos Complement Format
    • Individual DC Offset Subtraction DAC at TIA Input for Each LED and Ambient Phase
    • Digital Ambient Subtraction at ADC Output
    • Programmable Transimpedance Gain:
      10 kΩ to 2 MΩ
    • Dynamic Range: 100 dB
    • Average Current Less Than 200 µA for PPG Signal Acquisition
  • Pulse Frequency: 10 SPS to 1000 SPS
  • Flexible Pulse Sequencing and Timing Control
  • Flexible Clock Options:
    • External Clocking:
      4-MHz to 60-MHz Input Clock
    • Internal Clocking: 4-MHz Oscillator
  • I2C Interface
  • Operating Temperature Range: –20°C to 70°C
  • 2.6-mm × 1.6-mm DSBGA Package, 0.5-mm Pitch
  • Supplies: Rx: 2 V to 3.6 V, Tx: 3 V to 5.25 V,
    IO: 1.8 V to 3.6 V
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The AFE4404 is an analog front-end (AFE) for optical bio-sensing applications, such as heart-rate monitoring (HRM) and saturation of peripheral capillary oxygen (SpO2). The device supports three switching light-emitting diodes (LEDs) and a single photodiode. The current from the photodiode is converted into voltage by the transimpedance amplifier (TIA) and digitized using an analog-to-digital converter (ADC). The ADC code can be read out using an I2C interface. The AFE also has a fully-integrated LED driver with a 6-bit current control. The device has a high dynamic range transmit and receive circuitry that helps with the sensing of very small signal levels.

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Technical documentation

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Type Title Date
* Data sheet AFE4404 Ultra-Small, Integrated AFE for Wearable, Optical, Heart-Rate Monitoring and Bio-Sensing datasheet (Rev. D) Dec. 01, 2016
User guide AFE4404 Development Guide (Rev. A) Dec. 17, 2015
Technical article Offset correction improves the next generation of heart-rate smart watches Aug. 24, 2015
Technical article A new way to illuminate the human condition Dec. 30, 2013
Technical article Oximeter signaling: There’s more than meets the eye Dec. 04, 2013
Technical article Virtual hospital implementation using a worn health monitor Nov. 13, 2013

Design & development

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Hardware development

document-generic User guide

The AFE4404EVM is intended for evaluating TI's AFE4404 device. The fully integrated AFE is ideally suited for pulse oximeter and heart rate monitoring applications.  It consists of a low noise receive channel and LED transmit section. The AFE4404 has a very highly configurable timing controller (...)

  • DB9 pulse oximeter sensor cable support
  • Acquire data at up to 1000 Hz in evaluation mode
  • USB based power and PC application connectivity
  • Access to all AFE4404 registers via an easy-to-use GUI
  • USB-based firmware upgrade option

Software development

SBAC134.ZIP (16 KB)
AFE4404 Linux Driver
SLAC718A.ZIP (5732 KB)
SLAC704C.ZIP (329247 KB)

Design tools & simulation

PSpice® for TI design and simulation tool
PSPICE-FOR-TI — PSpice® for TI is a design and simulation environment that helps evaluate functionality of analog circuits. This full-featured, design and simulation suite uses an analog analysis engine from Cadence®. Available at no cost, PSpice for TI includes one of the largest model libraries in the (...)
  • Leverages Cadence PSpice Technology
  • Preinstalled library with a suite of digital models to enable worst-case timing analysis
  • Dynamic updates ensure you have access to most current device models
  • Optimized for simulation speed without loss of accuracy
  • Supports simultaneous analysis of multiple products
  • (...)

CAD/CAE symbols

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DSBGA (YZP) 15 View options

Ordering & quality

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