Product details

Number of channels (#) 1 Total supply voltage (Min) (+5V=5, +/-5V=10) 2.5 Total supply voltage (Max) (+5V=5, +/-5V=10) 5.5 BW @ Acl (MHz) 145 Acl, min spec gain (V/V) 1 Slew rate (Typ) (V/us) 490 Architecture Fully Differential ADC Driver, Bipolar Vn at flatband (Typ) (nV/rtHz) 4.6 Iq per channel (Typ) (mA) 1.14 Rail-to-rail In to V-, Out Vos (offset voltage @ 25 C) (Max) (mV) 2 Operating temperature range (C) -40 to 85 Output current (Typ) (mA) 55 2nd harmonic (dBc) 133 3rd harmonic (dBc) 141 @ MHz 0.001 GBW (Typ) (MHz) 95 Input bias current (Max) (pA) 900000 Features Shutdown CMRR (Typ) (dB) 102
Number of channels (#) 1 Total supply voltage (Min) (+5V=5, +/-5V=10) 2.5 Total supply voltage (Max) (+5V=5, +/-5V=10) 5.5 BW @ Acl (MHz) 145 Acl, min spec gain (V/V) 1 Slew rate (Typ) (V/us) 490 Architecture Fully Differential ADC Driver, Bipolar Vn at flatband (Typ) (nV/rtHz) 4.6 Iq per channel (Typ) (mA) 1.14 Rail-to-rail In to V-, Out Vos (offset voltage @ 25 C) (Max) (mV) 2 Operating temperature range (C) -40 to 85 Output current (Typ) (mA) 55 2nd harmonic (dBc) 133 3rd harmonic (dBc) 141 @ MHz 0.001 GBW (Typ) (MHz) 95 Input bias current (Max) (pA) 900000 Features Shutdown CMRR (Typ) (dB) 102
SOIC (D) 8 19 mm² 3.91 x 4.9 VSSOP (DGK) 8 15 mm² 3 x 4.9
  • Fully Differential Architecture
  • Bandwidth: 145 MHz (AV = 1 V/V)
  • Slew Rate: 490 V/µs
  • HD2: –133 dBc at 10 kHz (1 VRMS,
    RL = 1 kΩ)
  • HD3: –141 dBc at 10 kHz (1 VRMS,
    RL = 1 kΩ)
  • Input Voltage Noise: 4.6 nV/√Hz
    (f = 100 kHz)
  • THD+N: –112dBc (0.00025%) at
    1 kHz (22-kHz BW, G = 1, 5 VPP)
  • Open-Loop Gain: 119 dB (DC)
  • NRI–Negative Rail Input
  • RRO–Rail-to-Rail Output
  • Output Common-Mode Control
    (with Low Offset)
  • Power Supply:
    • Voltage: +2.5 V (±1.25 V) to
      +5.5 V (±2.75 V)
    • Current: 1.14 mA/ch
  • Power-Down Capability: 20 µA (typical)
  • Fully Differential Architecture
  • Bandwidth: 145 MHz (AV = 1 V/V)
  • Slew Rate: 490 V/µs
  • HD2: –133 dBc at 10 kHz (1 VRMS,
    RL = 1 kΩ)
  • HD3: –141 dBc at 10 kHz (1 VRMS,
    RL = 1 kΩ)
  • Input Voltage Noise: 4.6 nV/√Hz
    (f = 100 kHz)
  • THD+N: –112dBc (0.00025%) at
    1 kHz (22-kHz BW, G = 1, 5 VPP)
  • Open-Loop Gain: 119 dB (DC)
  • NRI–Negative Rail Input
  • RRO–Rail-to-Rail Output
  • Output Common-Mode Control
    (with Low Offset)
  • Power Supply:
    • Voltage: +2.5 V (±1.25 V) to
      +5.5 V (±2.75 V)
    • Current: 1.14 mA/ch
  • Power-Down Capability: 20 µA (typical)

The THS4521, THS4522, and THS4524 family of devices are very low-power, fully differential amplifiers with rail-to-rail output and an input common-mode range that includes the negative rail. These amplifiers are designed for low-power data acquisition systems and high-density applications where power dissipation is a critical parameter, and provide exceptional performance in audio applications.

The family includes single FDA (THS4521), dual FDA (THS4522), and quad FDA (THS4524) versions.

These fully differential amplifiers feature accurate output common-mode control that allows for dc-coupling when driving analog-to-digital converters (ADCs). This control, coupled with an input common-mode range below the negative rail as well as rail-to-rail output, allows for easy interfacing between single-ended, ground-referenced signal sources. Additionally, these devices are ideally suited for driving both successive-approximation register (SAR) and delta-sigma (ΔΣ) ADCs using only a single +2.5V to +5V and ground power supply.

The THS4521, THS4522, and THS4524 family of fully differential amplifiers is characterized for operation over the full industrial temperature range from –40°C to +85°C.

The THS4521, THS4522, and THS4524 family of devices are very low-power, fully differential amplifiers with rail-to-rail output and an input common-mode range that includes the negative rail. These amplifiers are designed for low-power data acquisition systems and high-density applications where power dissipation is a critical parameter, and provide exceptional performance in audio applications.

The family includes single FDA (THS4521), dual FDA (THS4522), and quad FDA (THS4524) versions.

These fully differential amplifiers feature accurate output common-mode control that allows for dc-coupling when driving analog-to-digital converters (ADCs). This control, coupled with an input common-mode range below the negative rail as well as rail-to-rail output, allows for easy interfacing between single-ended, ground-referenced signal sources. Additionally, these devices are ideally suited for driving both successive-approximation register (SAR) and delta-sigma (ΔΣ) ADCs using only a single +2.5V to +5V and ground power supply.

The THS4521, THS4522, and THS4524 family of fully differential amplifiers is characterized for operation over the full industrial temperature range from –40°C to +85°C.

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Technical documentation

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Type Title Date
* Data sheet THS452x Very Low Power, Negative Rail Input, Rail-To-Rail Output, Fully Differential Amplifier datasheet (Rev. H) 18 Jun 2015
Circuit design High-speed overcurrent detection circuit (Rev. A) 17 Jan 2019
E-book The Signal e-book: A compendium of blog posts on op amp design topics 28 Mar 2017
Technical article How to minimize filter loss when you drive an ADC 20 Oct 2016
Application note Fully-Differential Amplifiers (Rev. E) 19 Sep 2016
Technical article Go differential to differentiate your precision design 11 Aug 2016
Technical article How to use a fully differential amplifier as a level shifter 13 Jul 2016
Technical article What you need to know about internal ESD protection on integrated circuits 02 Dec 2015
More literature Featured High Speed Differential Amplifiers 23 Oct 2012
Analog Design Journal Converting single-ended video to differential video in single-supply systems 16 Sep 2011
Analog Design Journal Using single-supply fully diff. amps with neg. input voltages to drive ADCs 15 Nov 2010
Application note DC Output Errors in a Fully-Differential Amplifier 25 May 2010
Analog Design Journal Using fully differential op amps as attenuators, Part 3 04 Oct 2009
EVM User's guide THS4521/45222/4524EVM User's Guide 16 Jul 2009
Analog Design Journal Using fully differential op amps as attenuators, Part 2 14 Jul 2009
Analog Design Journal Using fully differential op amps as attenuators, Part 1 01 May 2009
Analog Design Journal Analysis of fully differential amplifiers 11 Mar 2005
Analog Design Journal Designing for low distortion with high-speed op amps 02 Mar 2005
Application note Noise Analysis for High Speed Op Amps (Rev. A) 17 Jan 2005

Design & development

For additional terms or required resources, click any title below to view the detail page where available.

Evaluation board

REF6025EVM-PDK — REF6025 voltage reference evaluation module

The REF6025EVM-PDK is a platform for evaluating the performance of the REF6025 voltage reference. The evaluation kit brings out the burst mode performance of the device which is a key feature of the device.
Evaluation board

THS4521EVM — THS4521 evaluation module

The THS4521EVM is an evaluation module for the single, THS4521 in the D (8-lead SOIC) package.

The THS4521EVM is designed to quickly and easily demonstrate the functionality and versatility of the amplifier. The EVM is ready to connect to power, signal source, and test instruments through the use of (...)

Simulation model

THS4521 TINA-TI Reference Design (Rev. E)

SBOM341E.TSC (1619 KB) - TINA-TI Reference Design
Simulation model

THS4521 TINA-TI Spice Model (Rev. D)

SBOM342D.ZIP (16 KB) - TINA-TI Spice Model
Simulation model

THS4521 PSpice Model (Rev. E)

SBOM343E.ZIP (36 KB) - PSpice Model
Simulation tool

PSPICE-FOR-TI — PSpice® for TI design and simulation tool

PSpice® for TI is a design and simulation environment that helps evaluate functionality of analog circuits. This full-featured, design and simulation suite uses an analog analysis engine from Cadence®. Available at no cost, PSpice for TI includes one of the largest model libraries in the (...)
Simulation tool

TINA-TI — SPICE-based analog simulation program

TINA-TI provides all the conventional DC, transient and frequency domain analysis of SPICE and much more. TINA has extensive post-processing capability that allows you to format results the way you want them. Virtual instruments allow you to select input waveforms and probe circuit nodes voltages (...)
Calculation tool

TI FDA Calculator

SBOR022.ZIP (1639 KB)
Reference designs

TIDA-00499 — Transient and Digital Fault Recorder AFE Using Differential Amplifiers and HS ADC Reference Design

While Digital Fault Recorders (DFRs) can detect transients in 17/20 μs at 60/50 Hz, transient recorders capture disturbances that can peak and decay well within a microsecond. This reference design demonstrates the capturing of transient inputs at up to 1 MHz for DFR and 25 MHz for (...)
Reference designs

TIPD115 — Data Acquisition Optimized for Lowest Distortion, Lowest Noise, 18 bit, 1Msps Reference Design

This TI Verified Design is a high performance data acquisition system (DAQ) using an 18-bit SAR ADC, ADS8881 at a throughput of 1MSPS. This design has been optimized to provide the lowest noise & distortion solution for a full scale input sinewave of 10 KHz. This leads to a maximum possible (...)
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TIDA-00715 — High Dynamic-Range Headphone Driver Reference Design for Voltage-Output, Differential Audio DACs

A low THD+N amplifier signal chain for driving headphones is presented. The design walks through various factors to consider in order to optimize performance based on customer needs.
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TIDM-ULTRASONIC-WATER-FLOW-MEASUREMENT — Ultrasonic Water Flow Measurement Reference Design

This Ultrasonic Water Flow Measurement system is ideal for providing highly accurate measurement across wide flow ranges as low as 1.4gpm. The design is based on a single MCU with discrete analog components. It uses a unique propriety algorithm that improves robustness and performance in flow (...)
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TIPD117 — Dual Channel Data Acquisition System for Optical Encoders, 12 Bit, 1MSPS

This TI Precision Verified Design provides the theory, component selection, simulation, PCB design, and measurement details for a 12-bit 1-MSPS single supply dual channel simultaneous data acquisition system. This circuit achieves 73 dB SINAD for a 4.5 V differential signal at 2 KHz input (...)
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SOIC (D) 8 View options
VSSOP (DGK) 8 View options

Ordering & quality

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  • Ongoing reliability monitoring

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