Wireless ECG, SpO2, PTT and heart rate monitor reference design for medical and consumer wearables
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Key Document


This reference design is a simple, wearable, multi-parameter, patient monitor that uses a single-chip, biosensing front end, the AFE4900 device, for synchronized electrocardiography (ECG) and photoplethysmography (PPG) measurements. The measured data is transferred to a remote location using the CC2640R2F device (supporting BLE 4.2 and 5). The reference design is operated using a single CR3032 battery and provides a battery life of 30 days. The raw data is available for the user to calculate heart-rate, oxygen concentration in blood (SpO2), pulse-transit time (PTT), and ECG. Two onboard light-emitting diodes (LEDs) indicate low-battery detection and ECG lead-off detection for users.

  • Simple, wearable, multi-parameter, patient monitor for PPG and ECG
  • Provides raw data to calculate heart rate, SpO2, and PTT
  • Uses single-chip, biosensing front-end AFE4900 device for synchronized ECG and PPG measurements
    • PPG (Optical heart-rate monitoring and SpO2) supports four LEDs and three photodiodes (PDs), with digital ambient subtraction to improve signal-to-noise ratio (SNR)
    • ECG (LEAD I) signals
  • Integrated Arm® Cortex®-M3 and 2.4-GHz RF transceiver (CC2640R2F) supports wireless data transfer - BLE 4.2 and 5.0
  • Operated by CR3032 (3-V, 500-mA coin-cell battery), with battery life of 30 days using highly efficient DC/DC converters
  • Small form factor helps with easy adaptation to wearable applications

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Schematic/Block Diagram

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Design Files

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TI Devices (5)

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Part Number Name Product Family Sample & Buy Design Kits & Evaluation Modules
AFE4900  Ultra-low-power integrated AFE for wearable optical, electrical biosensing  Medical AFEs  Not Available View Design Kits & Evaluation Modules
CC2640R2F  SimpleLink™ 32-bit Arm Cortex-M3 Bluetooth® Low Energy wireless MCU with 128kB Flash and 275kB ROM  SimpleLink Solutions  Sample & Buy View Design Kits & Evaluation Modules
TPD1E10B06  Single-channel ESD in 0402 package with 10pF capacitance and 6-V breakdown  Circuit protection ICs  Sample & Buy View Design Kits & Evaluation Modules
TPS61099  0.7Vin Synchronous Boost Converter with 800 nA Ultra-Low Quiescent Current  Step-up (boost) regulators  Sample & Buy View Design Kits & Evaluation Modules
TPS63036  High Efficient Single Inductor Buck-Boost Converter with 1-A Switches  Buck-boost & inverting regulators  Sample & Buy View Design Kits & Evaluation Modules

CAD/CAE symbols

Part # Package | Pins CAD File (.bxl) STEP Model (.stp)
CC2640R2F Download Download
Download Download
Download -
Download Download
TPD1E10B06 Download Download
TPS61099 Download Download
Download -

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Technical documentation

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Application notes (3)
Title Type Size (KB) Date
PDF 8634 10 Jan 2019
PDF 692 02 Mar 2015
PDF 313 14 Jan 2015
User guides (1)
Title Type Size (KB) Date
PDF 7501 22 May 2019
Design files (6)
Title Type Size (KB) Date
ZIP 704 20 May 2019
ZIP 1030 20 May 2019
ZIP 930 20 May 2019
ZIP 5686 20 May 2019
ZIP 184 20 May 2019
ZIP 308 20 May 2019
More literature (1)
Title Type Size (KB) Date
ZIP 18908 17 Oct 2018
Related Tools & Software

Reference Designs (1)

Hardware development (1)

Name Part Number Tool Type
SimpleLink™ Bluetooth® Low Energy CC2640R2F wireless MCU LaunchPad™ development kit  LAUNCHXL-CC2640R2  Development kits 

Software development (1)

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