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REF50E

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Enhanced low-noise (0.5µVpp/V), low-drift (2.5ppm°/C), wide-VIN (42V) precision voltage reference

Product details

Rating Catalog VO (V) 2.5, 3, 4.096, 4.5, 5 Temp coeff (max) (ppm/°C) 2.5 Initial accuracy (max) (%) 0.025 Features Noise-reduction pin Iout/Iz (max) (mA) 10 Vin (min) (V) 2.7 Vin (max) (V) 42 Iq (typ) (mA) 0.34 Operating temperature range (°C) -40 to 125
Rating Catalog VO (V) 2.5, 3, 4.096, 4.5, 5 Temp coeff (max) (ppm/°C) 2.5 Initial accuracy (max) (%) 0.025 Features Noise-reduction pin Iout/Iz (max) (mA) 10 Vin (min) (V) 2.7 Vin (max) (V) 42 Iq (typ) (mA) 0.34 Operating temperature range (°C) -40 to 125
SOIC (D) 8 29.4 mm² 4.9 x 6
  • Low temperature drift (maximum):
    • Enhanced-grade (new): 2.5ppm/°C
    • High-grade: 3ppm/°C
    • Standard-grade: 8ppm/°C
  • High accuracy (maximum):
    • Enhanced-grade: 0.025%
    • High-grade: 0.05%
    • Standard-grade: 0.1%
  • Low noise:
    • Enhanced-grade: 0.5µVPP/V
    • High/standard-grade: 3µVPP/V
  • Excellent long-term stability:
    • 22ppm after first 1000 hours (SOIC-8)
    • 50ppm after first 1000 hours (VSSOP-8)
  • Wide input voltage support:
    • Enhanced-grade: 42V
    • High/standard-grade: 18V
  • High-output current: ±10mA
  • Temperature range: -40°C to 125°C
  • Low temperature drift (maximum):
    • Enhanced-grade (new): 2.5ppm/°C
    • High-grade: 3ppm/°C
    • Standard-grade: 8ppm/°C
  • High accuracy (maximum):
    • Enhanced-grade: 0.025%
    • High-grade: 0.05%
    • Standard-grade: 0.1%
  • Low noise:
    • Enhanced-grade: 0.5µVPP/V
    • High/standard-grade: 3µVPP/V
  • Excellent long-term stability:
    • 22ppm after first 1000 hours (SOIC-8)
    • 50ppm after first 1000 hours (VSSOP-8)
  • Wide input voltage support:
    • Enhanced-grade: 42V
    • High/standard-grade: 18V
  • High-output current: ±10mA
  • Temperature range: -40°C to 125°C

The REF50xx is a family of low-noise, low-drift, very high precision voltage references. The references are capable of both sinking and sourcing current, and have excellent line and load regulation.

Achieve excellent temperature drift (2.5ppm/°C) and high accuracy (0.025%) using proprietary design techniques. These features, combined with very low flicker noise (0.5µVPP/V), make the REF50xx family an excellent choice for use in high-precision data acquisition systems. REF50 family is available in enhanced grade (REF50xxEI), high grade (REF50xxI), and standard grade (REF50xxAI). The reference voltages are offered in 8-pin SOIC and VSSOP packages and are specified from –40°C to 125°C.

For detailed comparison across various grades, refer to .

The REF50xx is a family of low-noise, low-drift, very high precision voltage references. The references are capable of both sinking and sourcing current, and have excellent line and load regulation.

Achieve excellent temperature drift (2.5ppm/°C) and high accuracy (0.025%) using proprietary design techniques. These features, combined with very low flicker noise (0.5µVPP/V), make the REF50xx family an excellent choice for use in high-precision data acquisition systems. REF50 family is available in enhanced grade (REF50xxEI), high grade (REF50xxI), and standard grade (REF50xxAI). The reference voltages are offered in 8-pin SOIC and VSSOP packages and are specified from –40°C to 125°C.

For detailed comparison across various grades, refer to .

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Technical documentation

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* Data sheet REF50xx Low-Noise, Very Low Drift, Wide VIN Precision Voltage Reference datasheet (Rev. O) PDF | HTML 16 Oct 2025
Circuit design High-input impedance, true differential, AFE attenuator circuit for SAR ADCs (Rev. B) PDF | HTML 25 Sep 2024
Circuit design High-current battery monitor circuit: 0–10A, 0-10kHz, 18 bit (Rev. A) PDF | HTML 12 Sep 2024
Circuit design ±12 V-Spannungssensorschaltung mit isoliertem Verstärker und SAR-ADC mit Differenzeingang (Rev. A) PDF | HTML 22 Jul 2024
Circuit design 절연 증폭기와 차동 입력 SAR ADC를 지원하는 ±12V 전압 감지 회 로 (Rev. A) PDF | HTML 16 Jul 2024
Circuit design ±12-V voltage sensing circuit with an isolated amplifier and differential input (Rev. A) PDF | HTML 06 Jun 2024
Application note Voltage Reference Selection and Design Tips For Data Converters (Rev. B) PDF | HTML 09 Jan 2024
Application note Analog Time Gain Control (ATGC) Solutions for TI’s Ultrasound AFE PDF | HTML 18 May 2023
Application note Stacking the REF50xx for High-Voltage References (Rev. B) PDF | HTML 25 Apr 2023
E-book Tips and tricks for designing with voltage references (Rev. A) 07 May 2021
Application note Long-Term Drift in Voltage References PDF | HTML 25 Mar 2021
Application note Low-Noise Negative Reference Design with REF5025 01 Dec 2019
E-book Voltage Supervisor and Reset ICs: Tips, Tricks and Basics 28 Jun 2019
White paper Voltage reference selection basics white paper (Rev. A) 23 Oct 2018
Analog Design Journal Q3 2009 Issue Analog Applications Journal 24 Sep 2018
Analog Design Journal Q4 2009 Issue Analog Applications Journal 24 Sep 2018
Application brief Level Shifting Signals With Differential Amplifiers (Rev. A) 02 Apr 2018
White paper Voltage-reference impact on total harmonic distortion 01 Aug 2016
Analog Design Journal How the voltage reference affects ADC performance, Part 3 04 Oct 2009
Analog Design Journal How the voltage reference affects ADC performance, Part 2 14 Jul 2009
Application note Low Power Input and Reference Driver Circuit for ADS8318 and ADS8319 24 Jun 2009

Design & development

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Design tool

ADC-DAC-TO-VREF-SELECT-DESIGN-TOOL The ADC-TO-VREF-SELECT tool enables the pairing of TI ADCs, DACs, and series voltage references.

The ADC-TO-VREF-SELECT tool enables the pairing of TI analog-to-digital converters (ADCs) and series voltage references. Users can select an ADC device and the desired reference voltage, and the tool will list up to two voltage reference recommendations.
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PSpice® for TI is a design and simulation environment that helps evaluate functionality of analog circuits. This full-featured, design and simulation suite uses an analog analysis engine from Cadence®. Available at no cost, PSpice for TI includes one of the largest model libraries in the (...)
Reference designs

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This reference design provides a cost-effective design for multichannel battery formation and test applications. The design uses the C2000™ real-time microcontroller (MCU) with 16-channel simultaneous sampling precision ADC, which can be scaled up to support 8-channel cell testing. The design (...)
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