Wireless ECG, SpO2, PTT and heart rate monitor reference design for medical and consumer wearables


Design files


This reference design is a simple, wearable, multi-parameter, patient monitor that uses a single-chip, biosensing front end, AFE4900, for synchronized electrocardiography (ECG) and photoplethysmography (PPG) measurements. The measured data is transferred to a remote location using CC2640R2F (supporting BLE 4.2 and 5). The reference design is operated using a single CR3032 battery and provides a battery life of 30 days. The raw data is available for the user to calculate heart-rate, oxygen concentration in blood (SpO2), pulse-transit time (PTT), and ECG. Two onboard light-emitting diodes (LEDs) indicate low-battery detection and ECG lead-off detection for users.

  • Simple, wearable, multi-parameter, patient monitor for PPG and ECG
  • Provides raw data to calculate heart rate, SpO2, and PTT
  • Uses single-chip, biosensing front-end AFE4900 for synchronized ECG and PPG measurements
    • PPG (Optical heart-rate monitoring and SpO2) supports four LEDs and three photodiodes (PDs), with digital ambient subtraction to improve signal-to-noise ratio (SNR)
    • ECG (LEAD I) signals
  • Integrated Arm® Cortex®-M3 and 2.4-GHz RF transceiver (CC2640R2F) supports wireless data transfer - BLE 4.2 and 5.0
  • Operated by CR3032 (3-V, 500-mA coin-cell battery), with battery life of 30 days using highly efficient DC/DC converters
  • Small form factor helps with easy adaptation to wearable applications
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A fully assembled board has been developed for testing and performance validation only, and is not available for sale.

Design files & products

Design files

Download ready-to-use system files to speed your design process.


Reference design overview and verified performance test data

TIDRW34A.ZIP (704 K)

Detailed schematic diagram for design layout and components

TIDRW35A.ZIP (184 K)

Complete listing of design components, reference designators, and manufacturers/part numbers

TIDRW36A.ZIP (308 K)

Detailed overview of design layout for component placement

TIDRW38A.ZIP (5686 K)

Files used for 3D models or 2D drawings of IC components


Design file that contains information on physical board layer of design PCB

TIDRW37A.ZIP (1030 K)

PCB layer plot file used for generating PCB design layout


Includes TI products in the design and potential alternatives.

AC/DC & DC/DC converters (integrated FET)

TPS610990.7Vin Synchronous Boost Converter with 800 nA Ultra-Low Quiescent Current

Data sheet: PDF | HTML
AC/DC & DC/DC converters (integrated FET)

TPS63036High Efficient Single Inductor Buck-Boost Converter with 1-A Switches

Data sheet: PDF | HTML
AC/DC & DC/DC converters (integrated FET)

TPS639001.8-V to 5.5-V, 75-nA IQ buck-boost converter with input current limit and Dynamic Voltage Scaling

Data sheet: PDF | HTML
AC/DC & DC/DC converters (integrated FET)

TPS639015.5-V buck-boost converter with 75-nA operating IQ in WCSP package

Data sheet: PDF | HTML
Biosensing AFEs

AFE4900Ultra-low-power integrated AFE for wearable optical, electrical biosensing

Data sheet: PDF | HTML
ESD protection diodes

TPD1E10B0612-pF, ±5.5V, ±30-kV ESD protection diode in 0402 and SOD-523 package

Data sheet: PDF | HTML
Low-power 2.4-GHz products

CC2640R2FSimpleLink™ 32-bit Arm® Cortex®-M3 Bluetooth® 5.1 Low Energy wireless MCU with 128-kB flash

Data sheet: PDF

Start development


Technical documentation

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Type Title Date
* Design guide Wireless ECG, SpO2, PTT and Heart Rate Monitor Reference Design (Rev. B) PDF | HTML Oct. 05, 2020
Technical article VIDEO: Wearable, wireless patient monitoring demo with Bluetooth 5 PDF | HTML Jun. 27, 2019
Technical article Designing compact, efficient and high performing multiparameter patient monitors PDF | HTML Jun. 25, 2019
Application note Measuring CC13xx and CC26xx current consumption (Rev. D) PDF | HTML Jan. 10, 2019
Technical article No strings attached: Creating next-generation wireless patient monitors PDF | HTML Jun. 29, 2018
Technical article Optical heart-rate sensors for biometric wearables PDF | HTML May 03, 2018
Application note How to Design an SpO2 and OHRM System Using AFE4403 Mar. 02, 2015
Application note Understanding Lead-Off Detection in ECG (Rev. A) Jan. 14, 2015

Related design resources

Hardware development

LAUNCHXL-CC2640R2 CC2640R2 LaunchPad™ development kit for SimpleLink™ Bluetooth® Low Energy wireless MCU

Reference designs

TIDA-010029 Wearable, 16-phase multi-sensor SpO2 and heart rate monitor (HRM) reference design with Bluetooth® 5

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