The TLV360x are specified for operation from 2.4 V to 5.5 V. While most applications will require single supply operation where VEE is connected to the ground plane and VCC is connected to the intended power supply level, the comparators can also be operated with split supplies. One caution when using split supplies is that the output logic levels are determined by the VCC and VEE levels. For example, if split supplies of +/- 2.5V are used, the output levels will be 2.5V and -2.5V accordingly. In addition, the logic level of the LE/HYS pin will also be referenced to VEE. This means that the external hysteresis resistor on the TLV3603-Q1 needs to be connected between the LE/HYS pin and VEE (not to ground) for proper operation.
Regardless of single supply or split supply operation, proper decoupling capacitors are required. It is recommended to use a scheme of multiple, low-ESR ceramic capacitors from the supply pins to the ground plane for optimum performance. A good combination would be 100 pF, 10 nF, and 1 uF with the lowest value capacitor closest to the comparator.