Product details

Applications Optical-HRM Number of input channels 3 Resolution (Bits) 24 Number of LEDs 4 Interface type SPI, I2C Operating temperature range (C) -20 to 70
Applications Optical-HRM Number of input channels 3 Resolution (Bits) 24 Number of LEDs 4 Interface type SPI, I2C Operating temperature range (C) -20 to 70
  • Accurate, Continuous Heart-Rate Monitoring:
    • Up to 100-dB Dynamic Range for Accurate Heart-Rate Detection
    • Low Current for Continuous Operation on a Wearable Device With a Typical Value:
      • 30 µA for an LED, 25 µA for the Receiver
  • Transmitter:
    • 4 LEDs in Common Anode Configurations
    • 8-Bit Programmable LED Current to 200 mA
    • Mode to Fire Two LEDs in Parallel
    • Programmable LED On-Time
    • Simultaneous Support of 3 LEDs for Optimized SpO2, HRM, or Multiwavelength HRM
    • Average Current of 30 µA Adequate for a Typical Heart-Rate Monitoring Scenario:
      • 20-mA Setting, 60-µs Pulse Duration,
        25-Hz Sampling Rate
  • Receiver:
    • Supports 3 Time-Multiplexed PD Inputs
    • 24-Bit Representation of Current Input From PD in Two’s-Complement Format
    • Individual DC Offset Subtraction DAC
      (Up to ±127-µA Range) at TIA Input for Each LED, Ambient
    • Digital Ambient Subtraction at ADC Output
    • Transimpedance Gain: 10 kΩ to 2 MΩ
    • Noise Filtering With Programmable Bandwidth
    • Receiver Operates at Approximately 1-µA/Hz Sampling Rate (Example, 25 µA at 25 Hz)
    • Hardware Power-Down Mode: Approximately 0-µA Current
  • Flexible Pulse Sequencing and Timing Control
  • Clocking Via External Clock or Internal Oscillator
  • FIFO With 128-Sample Depth:
    • Programmable Partitioning Across Phases
  • Pin-Selectable I2C, SPI Interface
  • Operating Temperature Range: –20°C to +70°C
  • 2.6-mm × 2.1-mm, 0.4-mm Pitch DSBGA Package
  • Supplies:
    • Tx: 3 V to 5.25 V
    • Rx: 1.8 V to 1.9 V (LDO Bypass),
      2.0 V to 3.6 V (LDO Enabled)
    • IO: 1.7 V to Rx_SUP
  • Accurate, Continuous Heart-Rate Monitoring:
    • Up to 100-dB Dynamic Range for Accurate Heart-Rate Detection
    • Low Current for Continuous Operation on a Wearable Device With a Typical Value:
      • 30 µA for an LED, 25 µA for the Receiver
  • Transmitter:
    • 4 LEDs in Common Anode Configurations
    • 8-Bit Programmable LED Current to 200 mA
    • Mode to Fire Two LEDs in Parallel
    • Programmable LED On-Time
    • Simultaneous Support of 3 LEDs for Optimized SpO2, HRM, or Multiwavelength HRM
    • Average Current of 30 µA Adequate for a Typical Heart-Rate Monitoring Scenario:
      • 20-mA Setting, 60-µs Pulse Duration,
        25-Hz Sampling Rate
  • Receiver:
    • Supports 3 Time-Multiplexed PD Inputs
    • 24-Bit Representation of Current Input From PD in Two’s-Complement Format
    • Individual DC Offset Subtraction DAC
      (Up to ±127-µA Range) at TIA Input for Each LED, Ambient
    • Digital Ambient Subtraction at ADC Output
    • Transimpedance Gain: 10 kΩ to 2 MΩ
    • Noise Filtering With Programmable Bandwidth
    • Receiver Operates at Approximately 1-µA/Hz Sampling Rate (Example, 25 µA at 25 Hz)
    • Hardware Power-Down Mode: Approximately 0-µA Current
  • Flexible Pulse Sequencing and Timing Control
  • Clocking Via External Clock or Internal Oscillator
  • FIFO With 128-Sample Depth:
    • Programmable Partitioning Across Phases
  • Pin-Selectable I2C, SPI Interface
  • Operating Temperature Range: –20°C to +70°C
  • 2.6-mm × 2.1-mm, 0.4-mm Pitch DSBGA Package
  • Supplies:
    • Tx: 3 V to 5.25 V
    • Rx: 1.8 V to 1.9 V (LDO Bypass),
      2.0 V to 3.6 V (LDO Enabled)
    • IO: 1.7 V to Rx_SUP

TheAFE4410is an analog front-end for optical biosensing applications, such as heart rate monitoring (HRM). The device supports a maximum of four switching light-emitting diodes (LEDs) and a maximum of three photodiodes (PDs). The electrical current from the photodiode is converted into voltage by the transimpedance amplifier (TIA) and digitized using an analog-to-digital converter (ADC). The ADC code is stored in a 128-sample first-in, first-out block (FIFO) with programmable depth. The FIFO can be read out using either an I2C interface or a serial peripheral interface (SPI). The AFE also has a fully integrated LED driver with 8-bit current control. The device has high dynamic range transmit-and-receive circuitry offering a dynamic range of up to 100 dB that enables accurate heart ratesensing. The AFE achieves extremely low current levels by operating an ultralow power (ULP) mode set by using the ENABLE_ULP register bit.


TheAFE4410is an analog front-end for optical biosensing applications, such as heart rate monitoring (HRM). The device supports a maximum of four switching light-emitting diodes (LEDs) and a maximum of three photodiodes (PDs). The electrical current from the photodiode is converted into voltage by the transimpedance amplifier (TIA) and digitized using an analog-to-digital converter (ADC). The ADC code is stored in a 128-sample first-in, first-out block (FIFO) with programmable depth. The FIFO can be read out using either an I2C interface or a serial peripheral interface (SPI). The AFE also has a fully integrated LED driver with 8-bit current control. The device has high dynamic range transmit-and-receive circuitry offering a dynamic range of up to 100 dB that enables accurate heart ratesensing. The AFE achieves extremely low current levels by operating an ultralow power (ULP) mode set by using the ENABLE_ULP register bit.


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Technical documentation

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Type Title Date
* Data sheet AFE4410 Ultra-Small, Integrated AFE With FIFO for Wearable, Continuous Optical Heart-Rate Monitoring and Biosensing datasheet (Rev. B) 31 Jul 2019
Technical article 10 lessons learned from 50-plus biometric wearable product development cycles 21 May 2018
Technical article Optical heart-rate sensors for biometric wearables 03 May 2018
Technical article Offset correction improves the next generation of heart-rate smart watches 24 Aug 2015
Technical article A new way to illuminate the human condition 30 Dec 2013

Design & development

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Evaluation board

AFE4403EVM — AFE4403 Integrated AFE for Heart-Rate Monitors and Pulse Oximeters Evaluation Module

The AFE4403EVM is intended for evaluating the AFE4403 device. The fully integrated AFE is ideally suited for Pulse Oximeter and Heart rate monitoring applications and consists of low noise receive channel, the LED transmit section and diagnostics for sensor and LED fault detection. The AFE4403 has a (...)

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Evaluation board

AFE4410EVM — AFE4410 Integrated AFE With FIFO for Wearable Optical Heart-Rate Monitoring Evaluation Module

The AFE4410 is an analog front end (AFE) for optical biosensing applications, such as heart-rate monitoring (HRM) and saturation of peripheral capillary oxygen (SpO2). The device supports four switching light-emitting diodes (LEDs) and three photodiodes. The current from the photodiode is converted (...)

Evaluation board

AFE4490SPO2EVM — AFE4490 Integrated Analog Front End (AFE) for Pulse Oximeters Evaluation Module

The AFE44x0SPO2EVM is intended for evaluating AFE4400 and AFE4490 devices. The family of devices are fully integrated AFE ideally suited for Pulse Oximeter applications and consist of low noise receive channel, the LED transmit section and diagnostics for sensor and LED fault detection. The (...)

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PSpice® for TI is a design and simulation environment that helps evaluate functionality of analog circuits. This full-featured, design and simulation suite uses an analog analysis engine from Cadence®. Available at no cost, PSpice for TI includes one of the largest model libraries in the (...)
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