Product details


Applications Optical-HRM, 1-lead ECG Number of input channels 4 Resolution (Bits) 24 Number of LEDs 6 Interface type I2C Operating temperature range (C) -40 to 85 open-in-new Find other Biosensing AFEs


  • Supports signal acquisition of up to 24 phases
  • Flexible allocation of 6 LED, 4 PD in each PPG phase
  • Synchronized PPG/ECG signal acquisition with each phase configurable as PPG or ECG, and at different data rates
  • Synchronized PPG/ECG supports up to 1 kHz data rate
  • ECG-only mode supports up to 4 kHz data rate
  • PPG signal chain:
    • System SNR up to 108-dB at 16 µA PD current
    • Low current for continuous operation on a wearable device with a typical value: 15 µA for an LED, 20 µA for the receiver
  • PPG Transmitter:
    • Supports common anode LED configuration
    • 8-Bit programmable LED current with range adjustable from 25 mA to 250 mA
    • Mode to fire two LEDs in parallel with independent per-phase current control
    • Programmable LED on-time per-phase
    • Simultaneous support of 6 LEDs for SpO2, HRM, or multi-wavelength HRM
  • PPG Receiver:
    • Supports 4 time-multiplexed photodiode inputs
    • 2 parallel receivers to sample two PD channels simultaneously
    • Individual ambient offset subtraction DAC at each TIA Input with 8-bit per-phase control and range adjustable up to 255-µA
    • Individual LED offset subtraction DAC at each TIA input with 5-bit per-phase control and
      15.5-µA range
    • Close to 100 dB ambient rejection up to 10 Hz
    • Noise filtering with programmable bandwidth
    • Transimpedance Gain: 3.7 kΩ to 1 MΩ
  • ECG Signal Chain
    • 1-lead ECG with RLD output for bias
    • INA gain programmable from 1.6 – 13
    • <1 µVrms input noise (in a 1-150 Hz bandwidth) at 4-kHz sample rate
    • Integrated 450 Hz Low Pass Filter
    • AC, DC lead-off detect with 3.125-100 nA current and programmable interrupt
  • Supports external clock and internal oscillator modes
  • Option to acquire data synchronized with a system master clock
  • Automatic cancellation of DC from ambient, LED
  • FIFO with 128-sample depth
  • I2C interface
  • 2.6-mm × 2.1-mm DSBGA, 0.4-mm pitch
  • Supplies: Rx: 1.7 V-1.9 V (LDO bypass); 1.9 V-3.6 V (LDO enabled), Tx: 3 V-5.5 V, IO: 1.7-3.6 V
  • Supports operation with 2 supplies - 1.8 V, 5 V
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The AFE49I30 is an analog front-end for optical bio-sensing/ PPG and ECG measurement applications. The device supports up to six switching light-emitting diodes (LEDs) and up to four photodiodes. Up to 24 signal phases can be defined and the PPG or ECG signals can be acquired from each phase in a synchronized manner.

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Technical documentation

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Type Title Date
* Data sheet AFE49I30 Ultra-Small, Integrated AFE With FIFO for Multi-Sensor Wearable, Optical Heart-Rate Monitoring and Bio-sensing datasheet Apr. 13, 2020
Technical article Offset correction improves the next generation of heart-rate smart watches Aug. 24, 2015
Technical article A new way to illuminate the human condition Dec. 30, 2013
Technical article Oximeter signaling: There’s more than meets the eye Dec. 04, 2013
Technical article Virtual hospital implementation using a worn health monitor Nov. 13, 2013

Design & development

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Hardware development


The AFE44S30 evaluation module (EVM) is a platform for evaluating the AFE44S30 device, which is an analog front end (AFE) for optical biosensing applications, such as heart-rate monitoring (HRM) and saturation of peripheral capillary oxygen (SpO2). AFE44S30 supports eight switching (...)

  • Acquire data at up to 1000 SPS in evaluation mode
  • USB-based power and PC application connectivity
  • Access to all AFE44S30 registers
  • USB-based firmware upgrade option

The AFE49I30 evaluation module (EVM) is a platform for expediting and evaluating system development activities related to the AFE49I30 product. AFE49I30 is an analog front end (AFE) for optical biosensing applications, such as heart-rate monitoring (HRM) and saturation of peripheral capillary oxygen (...)

  • Acquire data at up to 1000 SPS in evaluation mode
  • USB-based power and PC application connectivity
  • Access to all AFE49I30 registers
  • USB-based firmware upgrade option

Software development

B SECUR ECG algorithms and electrode design services
Provided by B Secur HeartKey is a powerful and accurate set of ECG algorithms, ready for integration into the next generation low power low memory consumer / IoT & medical devices such as smartwatches, smart clothing, medical, automotive, smart home devices and hand-held devices. HeartKey is comprised of advanced (...)

Design tools & simulation

PSpice® for TI design and simulation tool
PSPICE-FOR-TI — PSpice® for TI is a design and simulation environment that helps evaluate functionality of analog circuits. This full-featured, design and simulation suite uses an analog analysis engine from Cadence®. Available at no cost, PSpice for TI includes one of the largest model libraries in the (...)
  • Leverages Cadence PSpice Technology
  • Preinstalled library with a suite of digital models to enable worst-case timing analysis
  • Dynamic updates ensure you have access to most current device models
  • Optimized for simulation speed without loss of accuracy
  • Supports simultaneous analysis of multiple products
  • (...)

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