Product details


Number of channels (#) 1 Total supply voltage (Min) (+5V=5, +/-5V=10) 2.7 Total supply voltage (Max) (+5V=5, +/-5V=10) 5.4 BW @ Acl (MHz) 620 Acl, min spec gain (V/V) 1 Slew rate (Typ) (V/us) 1500 Vn at flatband (Typ) (nV/rtHz) 2.2 Iq per channel (Typ) (mA) 10.1 Rail-to-rail In to V-, Out Vos (offset voltage @ 25 C) (Max) (mV) 0.45 Operating temperature range (C) -40 to 125 Output current (Typ) (mA) 100 2nd harmonic (dBc) 95 3rd harmonic (dBc) 90 GBW (Typ) (MHz) 850 Input bias current (Max) (pA) 13000000 @ MHz 10 CMRR (Typ) (dB) 100 open-in-new Find other Fully differential amplifiers

Package | Pins | Size

VQFN (RGT) 16 9 mm² 3 x 3 open-in-new Find other Fully differential amplifiers


  • AEC-Q100 qualified for automotive applications:
    • Temperature grade 1: –40°C to +125°C, TA
  • Bandwidth: 500 MHz (G = 2 V/V)
  • Gain bandwidth product: 850 MHz
  • Slew rate: 1500 V/µs
  • HD2: –95 dBc at 10 MHz (2 VPP, RL = 500 Ω)
  • HD3: –90 dBc at 10 MHz (2 VPP, RL = 500 Ω)
  • Input voltage noise: 2.2 nV/Hz (f > 100 kHz)
  • Low offset drift: ±0.5 µV/°C (typ)
  • Negative rail input (NRI)
  • Rail-to-rail output (RRO)
  • Power supply:
    • Single-supply voltage range: 2.7 V to 5.4 V
    • Split-supply voltage range: ±1.35 V to ±2.7 V
    • Quiescent current: 10.1 mA (5-V supply)
  • Power-down capability: 2 µA (typ)

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The THS4541-Q1 is a low-power, voltage-feedback, fully differential amplifier (FDA) with an input common-mode range below the negative rail, and rail-to-rail output. Designed for low-power data acquisition systems where high density is critical in a high-performance analog-to-digital converter (ADC) or digital-to-analog converter (DAC) interface design.

The THS4541-Q1 features the negative-rail input required when interfacing a DC-coupled, ground-centered, source signal. This negative-rail input, with rail-to-rail output, allows for easy interface between single-ended, ground-referenced, bipolar signal sources and a wide variety of successive approximation register (SAR), delta-sigma (ΔΣ), or pipeline ADCs using only a single 2.7-V to 5.4-V power supply.

The THS4541-Q1 is characterized for operation over the wide temperature range of –40°C to +125°C and is available in a 16-pin VQFN package both with and without wettable flanks. The package with wettable flanks eases post-assembly visual inspection and is available as the THS4541W-Q1.

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Technical documentation

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Type Title Date
* Data sheet THS4541-Q1 Negative Rail Input, Rail-to-Rail Output, Precision, 850-MHz Fully Differential Amplifier datasheet (Rev. B) Nov. 15, 2019
E-book The Signal e-book: A compendium of blog posts on op amp design topics Mar. 28, 2017
Technical article How to minimize filter loss when you drive an ADC Oct. 20, 2016
Application note Design for a Wideband Differential Transimpedance DAC Output (Rev. A) Oct. 17, 2016
Technical article Go differential to differentiate your precision design Aug. 11, 2016
Technical article How to use a fully differential amplifier as a level shifter Jul. 13, 2016
Technical article What you need to know about internal ESD protection on integrated circuits Dec. 02, 2015
Application note Design for a Wideband Differential Transimpedance DAC Output Apr. 18, 2008
Application note Noise Analysis for High Speed Op Amps (Rev. A) Jan. 17, 2005

Design & development

For additional terms or required resources, click any title below to view the detail page where available.

Hardware development


The DEV-ADC34J22 is a four-channel, 50MSPS ADC Module designed to integrate with Altera’s HSMC standard. The DEV-ADC34J22 features TI’s new JESD204B compliant ADC34J22 Analog Digital Converter (ADC), with clocking conditioning using TI’s LMK04828 jitter cleaner. It provides (...)


Board Features

  • Texas Instruments ADC34J22 Analog to Digital Converter
  • 4 channel, 12bit, 50 MSPS, JESD204B compliant ADC module
  • Two RF AC coupled input channels
  • Two Analog DC coupled input channels
  • External clock input
  • External trigger input
  • On board TI LMK04828B Dual Loop
  • Clock Jitter Cleaner Reference (...)
document-generic User guide

The THS4541RGT EVM is an evaluation module for the single THS4541 amplifier in the RGT package. This evaluation module is designed to quickly and easily demonstrate the functionality and versatility of the amplifier. The EVM is ready to connect to power, signal source, and test instruments (...)

  1. Configured for split-supply operation and easily modified for single supply.
  2. Default gain of 2 configuration can easily be reconfigured for other gains.
  3. Designed for easy connection to standard 50-Ω input/output impedance test equipment.
  4. Inputs and outputs include SMA connectors.

Design tools & simulation

PSpice® for TI design and simulation tool
PSPICE-FOR-TI — PSpice® for TI is a design and simulation environment that helps evaluate functionality of analog circuits. This full-featured, design and simulation suite uses an analog analysis engine from Cadence®. Available at no cost, PSpice for TI includes one of the largest model libraries in the (...)
  • Leverages Cadence PSpice Technology
  • Preinstalled library with a suite of digital models to enable worst-case timing analysis
  • Dynamic updates ensure you have access to most current device models
  • Optimized for simulation speed without loss of accuracy
  • Supports simultaneous analysis of multiple products
  • (...)
SPICE-based analog simulation program
TINA-TI TINA-TI provides all the conventional DC, transient and frequency domain analysis of SPICE and much more. TINA has extensive post-processing capability that allows you to format results the way you want them. Virtual instruments allow you to select input waveforms and probe circuit nodes voltages (...)
document-generic User guide

Reference designs

High Perf Single Ended to Diff Active Interface for High Speed ADC Developed by Dallas Logic Corp
Provided by Dallas Logic Corporation This reference design uses the ADC34J22 12b 50Msps JESD204B data converter and the THS4541 fully differential amplifer to demonstrate how to design a high performance active interface for high speed ADCs.  This type of circuit can be used in sensor front end, motor control, and test and (...)
document-generic Schematic document-generic User guide

CAD/CAE symbols

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VQFN (RGT) 16 View options

Ordering & quality

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Support & training

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