Each DS320PR410 internal registers can be accessed through standard SMBus protocol. The DS320PR410 features one bank of channels, Channels 0–3. The SMBus secondary address pairs (one for each device) are determined at power up based on the configuration of the EQ0 / ADDR0 and EQ1 / ADDR1 pins. The pin state is read on power up, after the internal power-on reset signal is deasserted.

There are 16 unique SMBus secondary addresses that can be assigned to the device by placing external resistor straps on the EQ0 / ADDR0 and EQ1 / ADDR1 pins as shown in Table 3-3. When multiple DS320PR410 devices are on the same SMBus interface bus, each device must be configured with a unique SMBus secondary address.