Difference amplifiers

Featuring precision-matched resistor networks for high accuracy and wide input common-mode voltage range

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Our difference amplifiers are optimized for high-input common-mode voltage and common-mode rejection to measure small differential signals. TI's new generation of high-performance difference amplifiers use award-winning processes and precision technologies such as thin-film resistors and propietary e-Trim™ technology to provide exceptional DC performance.

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High common-mode voltage (≥50 V)

Maximize input signal range with high common-mode voltage capability.

High CMRR (≥80 dB)

Reduce unwanted noise with a high common-mode-rejection ratio.

Low offset (≤250 µV)

Improve DC accuracy with low offset and high-precision performance.

Small packages (≤16 mm2)

Reduce board size without compromising performance.

Automotive grade

Complete your automotive design with AEC-Q100 qualified difference amplifiers.

Find a difference amplifier that best fits your design needs

Difference amplifiers

Low-power, greater than 1MΩ RIN, 13.5µA IQ, small-size attenuating difference amplifier

Approx. price (USD) 1ku | 0.145

Why choose our difference amplifiers?


High DC precision

Ensure long-term stability with zero-drift, eliminate package stress parameter shifts with e-trim, and maintain high CMRR and low gain error with highly matched 0.001% thin film resistors.


High common-mode input range

Enable high-voltage applications with accurate measurements at high common-mode voltages, up to ±550 V


Low power

Enable battery-powered applications with precision difference amplifiers with low quiescent current consumption down to 160 µA


Small packages

Reduce board size with leadless 3x3 mm WSON packages while maintaining industry leading precision

Technical resources

Analog Design Journal
Analog Design Journal
Precision signal-conditioning solutions for motor control with position feedback
This article compares three different precision signal path solutions on a position feedback application. High-performance difference amplifiers are used to achieve lowest output-referred offset and lower cost. 
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Application note
Application note
Analysis of Improved Howland Current Pump Configurations (Rev. A)
This article analyzes a few Improved Howland current pump configurations using difference amplifiers and provides recommendations on how to enhance their performance.
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Circuit design
Circuit design
High common-mode differential input voltage to ±10-V ADC input circuit
This article discusses advantages and disadvantages of using difference amplifiers to translate a signal with a high common mode voltage (Vcm) to a level that the ADC can accept.
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Design & development resources

Reference design
Shunt Based Ground Fault Protection for Inverters Powered from 100/110Vac Supply Reference Design

This is a reference design for detecting ground fault in inverter-based drives. Inverter current is measured on both DC-positive and DC-negative bus using shunt resistors. INA149 current sense amplifier having a common-mode voltage range of +275 V is used to measure current on DC-positive bus. (...)

Reference design
PM2.5 and PM10 Particle Sensor Analog Front-End for Air Quality Monitoring Reference Design

TIDA-00378 provides an analog front-end for measuring PM2.5 and PM10 particle matter. The reference design detects light scattered by particles suspended in air. A sample software algorithm is provided to convert the analog output of the design into a particle size and concentration measurement. (...)

Reference design
Analog Input Module for Industrial Outputs and Temperature Sensors Reference Design

This reference design that is precision verified implements an analog input module for industrial voltages, currents and temperature sensors.  For industrial outputs, the possible input ranges include: 4 to 20 mA, 0 to 20 mA, +/-25 mA, 0 to 5 V, 0 to 10 V, +/-5 V and +/-10 V. The design (...)