Low-power, 60-MHz, wide-supply-range fully differential amplifier


Product details


Number of channels (#) 1 Total supply voltage (Min) (+5V=5, +/-5V=10) 2.85 Total supply voltage (Max) (+5V=5, +/-5V=10) 12.6 BW @ Acl (MHz) 60 Acl, min spec gain (V/V) 1 Slew rate (Typ) (V/us) 230 Architecture Fully Differential ADC Driver, Bipolar Vn at flatband (Typ) (nV/rtHz) 4 Iq per channel (Typ) (mA) 0.78 Rail-to-rail In to V-, Out Vos (offset voltage @ 25 C) (Max) (mV) 0.25 Operating temperature range (C) -40 to 125 Output current (Typ) (mA) 27 2nd harmonic (dBc) 117 3rd harmonic (dBc) 124 GBW (Typ) (MHz) 60 Input bias current (Max) (pA) 600000 Features Shutdown CMRR (Typ) (dB) 110 open-in-new Find other Fully differential amplifiers

Package | Pins | Size

VQFN (RGT) 16 9 mm² 3 x 3 VSSOP (DGK) 8 15 mm² 3 x 4.9 WQFN (RUN) 10 4 mm² 2 x 2 open-in-new Find other Fully differential amplifiers


  • Bandwidth: 60 MHz (G = 1 V/V)
  • Slew Rate: 230 V/µs
  • Gain Bandwidth Product: 68 MHz
  • Voltage Noise:
    • 1/f Voltage Noise Corner: 8 Hz
    • Broadband Noise (≥ 500 Hz): 4 nV/√ Hz
  • Input Offset: ±250 µV (Maximum)
    • Drift: ±4 µV/°C (Maximum)
  • Supply Operating Range: 2.85 V to 12.6 V
  • Supply Current: 775 µA
  • Negative Rail Input (NRI)
  • Rail-to-Rail Output (RRO)
  • Very Low Harmonic Distortion:
    • HD2: –117 dBc at 2 VPP, 100 kHz
    • HD3: –124 dBc at 2 VPP, 100 kHz
  • 0.01% Settling (2-V Step): 90 ns
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The THS4561 fully differential amplifier (FDA) offers a simple interface from single-ended sources to the differential output required by precision analog-to-digital converters (ADCs). Designed for a very low,8-Hz, 1/f voltage noise corner and low, 130-dB total harmonic distortion (THD) while consuming only a775-µA quiescent current, the THS4561 is well suited for power-sensitive data acquisition (DAQ) systems where high performance is required with the best signal-to-noise ratio (SNR) and spurious-free dynamic range (SFDR) through the amplifier and ADC combination.

The THS4561 features the required negative rail input when interfacing a DC-coupled, ground-centered, source signal to a single-supply, differential-input ADC. Low DC error and drift terms support the emerging high-speed and high-resolution successive approximation register (SAR) and delta-sigma (ΔΣ) ADC input requirements. A 2.85-V to 12.6-V supply range with a flexible output common-mode setting with low headroom to the supplies supports a wide range of ADC input and digital-to-analog converter (DAC) output requirements.

The THS4561 device is characterized for operation from –40°C to +125°C.

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Technical documentation

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Type Title Date
* Data sheet THS4561 Low-Power, High Supply Range, 60-MHz, Fully Differential Amplifier datasheet (Rev. D) Feb. 01, 2021
Application note Differential input to differential output circuit using a fully-differential amp Jan. 07, 2019
Application note Single-ended input to differential output circuit using a fully-differential amp Jan. 07, 2019
Application note Attenuator Amplifier Design to Maximize the Input Voltage of Differential ADCs Jun. 14, 2018
User guide THS4561 EVM User's Guide Aug. 10, 2017
Technical article How to minimize filter loss when you drive an ADC Oct. 20, 2016
Technical article Go differential to differentiate your precision design Aug. 11, 2016
Technical article How to use a fully differential amplifier as a level shifter Jul. 13, 2016
Technical article What you need to know about internal ESD protection on integrated circuits Dec. 02, 2015
Application note Noise Analysis for High Speed Op Amps (Rev. A) Jan. 17, 2005

Design & development

For additional terms or required resources, click any title below to view the detail page where available.

Hardware development

document-generic User guide
The THS4561DGKEVM is an evaluation module (EVM) for the single THS4561 amplifier in the DGK (VSSOP-8) package. This EVM is designed to quickly and easily demonstrate the functionality and versatility of the amplifier. The THS4561DGKEVM is ready to connect to power, signal source, and test (...)
  • Configured for split-supply operation and easily modified for single supply
  • Default gain of 1 configuration is easily reconfigured for other gains
  • Designed for easy connection to standard 50-Ω input and output impedance test equipment
  • Inputs and outputs include SMA connectors

Design tools & simulation

SBOMAE3C.ZIP (42 KB) - PSpice Model
SBOMAE4C.TSC (36 KB) - TINA-TI Reference Design
SBOMAE5C.ZIP (11 KB) - TINA-TI Spice Model
SBOMBM0.TSC (94 KB) - TINA-TI Reference Design
SBOMBM1.TSC (1083 KB) - TINA-TI Reference Design
PSpice® for TI design and simulation tool
PSPICE-FOR-TI — PSpice® for TI is a design and simulation environment that helps evaluate functionality of analog circuits. This full-featured, design and simulation suite uses an analog analysis engine from Cadence®. Available at no cost, PSpice for TI includes one of the largest model libraries in the (...)
  • Leverages Cadence PSpice Technology
  • Preinstalled library with a suite of digital models to enable worst-case timing analysis
  • Dynamic updates ensure you have access to most current device models
  • Optimized for simulation speed without loss of accuracy
  • Supports simultaneous analysis of multiple products
  • (...)
SPICE-based analog simulation program
TINA-TI TINA-TI provides all the conventional DC, transient and frequency domain analysis of SPICE and much more. TINA has extensive post-processing capability that allows you to format results the way you want them. Virtual instruments allow you to select input waveforms and probe circuit nodes voltages (...)
document-generic User guide

Reference designs

Battery Tester Reference Design for High Current Applications
TIDA-01040 — Li-Ion battery formation and electrical testing require accurate voltage and current control, usually to better than ±0.05% over the specified temperature range.  This reference design proposes a solution for high-current (up to 50 A) battery tester applications supporting input (bus (...)
document-generic Schematic
Battery tester reference design for multi-phase high-precision 0.5 to 100 A battery formation
TIDA-01041 — This reference design provides a multi-phase solution for a wide range of current battery test applications. Leveraging the dual phase buck/boost controller LM5170's daisy chain configuration gives the design the ability to achieve 100A charging/discharging rates. Utilizing high accuracy constant (...)
document-generic Schematic
Modular battery tester reference design for 50-A, 100-A, and 200-A applications
TIDA-01042 — This reference design provides a modular battery test solution allowing users to have the flexibility to test batteries at different current levels with one design. This design leverages the TIDA-01041 reference design by providing two 100-A battery testers that can work independently or be (...)
document-generic Schematic
Reference Design Maximizing Signal Dynamic Range for True 10 Vpp Differential Input to 20 bit ADC
TIDA-01057 — This reference design is designed for high performance data acquisition(DAQ) systems to improve the dynamic range of 20 bit differential input ADCs. Many DAQ systems require the measurement capability at a wide FSR (Full Scale Range) in order to obtain sufficient signal dynamic range. Many earlier (...)
document-generic Schematic

CAD/CAE symbols

Package Pins Download
QFN (RUN) 10 View options
VQFN (RGT) 16 View options
VSSOP (DGK) 8 View options

Ordering & quality

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Support & training

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